Хайлова Людмила Самуиловна
старший научный сотрудник

Избранные статьи

1. Rokitskaya Tatyana I., Khailova Ljudmila S., Strelnik Anna G., Kotova Elena A., Mironov Vladimir F., Tatarinov Dmitry A., Antonenko Yuri N. (2025) Replacement of phenyl substituents at phosphorus by hexyl ones in 2-(2-hydroxyaryl)vinylphosphonium salts can tune the nature of the induced proton transport through lipid membranes. Biochimica et Biophysica Acta - Biomembranes, >>


2. Firsov Alexander M., Khailova Ljudmila S., Nazarov Pavel A., Ukraintsev Maxim, Kirsanov Roman S., Kovalchuk Sergei I., Lyamzaev Konstantin G., Panteleeva Alisa A., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2025) 2-Azido-4-nitrophenol is a light-sensitive antibacterial protonophore. Bioelectrochemistry, >>


3. Antonenko Yuri N., Rudenko Alexander Y., Khailova Ljudmila S., Firsov Alexander M., Kirsanov Roman S., Lyamzaev Konstantin G., Panteleeva Alisa A., Popova Lyudmila B., Mariasina Sofia S., Kotova Elena A., Polshakov Vladimir I. (2025) Cyazofamid-dessulfonamide (CCIM) is an anionic uncoupler of oxidative phosphorylation in mitochondria and a protonophore on lipid membranes. Biochemical and Biophysical Research Communications, >>


4. Kirsanov Roman S., Khailova Ljudmila S., Krasnov Vladimir S., Firsov Alexander M., Lyamzaev Konstantin G., Panteleeva Alisa A., Popova Lyudmila B., Nazarov Pavel A., Tashlitsky Vadim N., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2024) Spontaneous reversal of small molecule-induced mitochondrial uncoupling: the case of anilinothiophenes. FEBS Journal, >>


5. Khailova Ljudmila S., Kirsanov Roman S., Rokitskaya Tatyana I., Krasnov Vladimir S., Korshunova Galina A., Kotova Elena A., Yuri N.Antonenko (2024) Mitochondrial uncoupling caused by a wide variety of protonophores is differently sensitive to carboxyatractyloside in rat heart and liver mitochondria. Biochimica et Biophysica Acta - Bioenergetics, >>


6. Antonenko YN, Veselov IM, Rokitskaya TI, Vinogradova DV, Khailova LS, Kotova EA, Maltsev AV, Bachurin SO, Shevtsova EF (2024) Neuroprotective thiourea derivative uncouples mitochondria and exerts weak protonophoric action on lipid membranes. Chemico-Biological Interactions, >>


7. Kirsanov Roman S., Khailova Ljudmila S., Rokitskaya Tatyana I., Lyamzaev Konstantin G., Panteleeva Alisa A., Nazarov Pavel A., Firsov Alexander M., Iaubasarova Iliuza R., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2024) Synthesis of Triphenylphosphonium-Linked Derivative of 3,5-Ditert-butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler. ACS Omega, >>


8. Rokitskaya Tatyana, Kirsanov Roman S., Khailova Ljudmila S., Panteleeva Alisa A., Lyamzaev Konstantin G., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2024) Methylation of Phenyl Rings in Ester‐Stabilized Phosphorus Ylides Vastly Enhances Their Protonophoric Activity. Chembiochem : a European journal of chemical biology, >>


9. Khailova Ljudmila S., Krasnov Vladimir S., Kirsanov Roman S., Popova Lyudmila B., Tashlitsky Vadim N., Kotova Elena A., Antonenko Yuri N. (2023) The transient character of mitochondrial uncoupling by the popular fungicide fluazinam is specific for liver. Archives of Biochemistry and Biophysics, >>


10. Rokitskaya Tatyana I., Khailova Ljudmila S., Korshunova Galina A., Antonenko Yuri N. (2023) Efficiency of mitochondrial uncoupling by modified butyltriphenylphosphonium cations and fatty acids correlates with lipophilicity of cations: Protonophoric vs leakage mechanisms. Biochimica et Biophysica Acta - Biomembranes, >>


11. Rokitskaya Tatyana I., Firsov Alexander M., Khailova Ljudmila S., Kotova Elena A., Yuri N.Antonenko (2023) Selectivity of cation transport across lipid membranes by the antibiotic salinomycin. Biochimica et Biophysica Acta - Biomembranes, >>


12. Zorova Ljubava D., Pevzner Irina B., Khailova Ljudmila S., Korshunova Galina A., Kovaleva Marina A., Kovalev Leonid I., Serebryakova Marina V., Silachev Denis N., Sudakov Roman V., Zorov Savva D., Rokitskaya Tatyana I., Popkov Vasily A., Plotnikov Egor Y. (2023) Mitochondrial ATP Synthase and Mild Uncoupling by Butyl Ester of Rhodamine 19, C4R1. ANTIOXIDANTS, >>


13. Kirsanov Roman S., Khailova Ljudmila S., Rokitskaya Tatyana I., Iaubasarova Iliuza R., Nazarov Pavel A., Panteleeva Alisa A., Lyamzaev Konstantin G., Popova Lyudmila B., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2023) Ester-stabilized phosphorus ylides as protonophores on bilayer lipid membranes, mitochondria and chloroplasts. Bioelectrochemistry, >>


14. Rokitskaya T.I., Arutyunyan A.M., Khailova Ljudmila S., Kataeva Alisa D., Firsov Alexander M., Kotova Elena A., Antonenko Yuri N. (2022) Usnic Acid-Mediated Exchange of Protons for Divalent Metal Cations across Lipid Membranes: Relevance to Mitochondrial Uncoupling. International Journal of Molecular Sciences, >>


15. Firsov Alexander M., Khailova Ljudmila S., Rokitskaya Tatyana I., Kotova Elena A., Antonenko Yuri N. (2022) Antibiotic Pyrrolomycin as an Efficient Mitochondrial Uncoupler. Biochemistry (Moscow), >>


16. Фирсов А.М., Хайлова Л.С., Рокицкая Т.И., Котова Е.А., Антоненко Ю.Н. (2022) Антибиотик пирроломицин является эффективным разобщителем митохондрий. Biochemistry (Moscow), >>


17. Krasnov Vladimir S., Kirsanov Roman S., Khailova Ljudmila S., Popova Lyudmila B., Lyamzaev Konstantin G., Firsov Alexander M., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2022) Alkyl esters of 7-hydroxycoumarin-3-carboxylic acid as potent tissue-specific uncouplers of oxidative phosphorylation: Involvement of ATP/ADP translocase in mitochondrial uncoupling. Archives of Biochemistry and Biophysics, >>


18. Grivennikova Vera G., Khailova Ljudmila S., Zharova Tatyana V., Kotova Elena A., Antonenko Yuri N. (2022) Inhibition of respiratory complex I by 6-ketocholestanol: Relevance to recoupling action in mitochondria. Biochimica et Biophysica Acta - Bioenergetics, >>


19. Antonenko Yuri N., Jędrzejczyk M., Rokitskaya Tatyana I., Khailova Ljudmila S., Kotova Elena A., Huczyński A. (2022) Rate of translocation across lipid bilayer of triphenylphosphonium-linked salinomycin derivatives contributes significantly to their K+/H+ exchange activity on membranes. Bioelectrochemistry, >>


20. Krasnov Vladimir S., Kirsanov Roman S., Khailova Ljudmila S., Firsov Alexander M., Nazarov Pavel A., Tashlitsky Vadim N., Korshunova Galina A., Kotova Elena A., Antonenko Yuri N. (2022) Alkyl esters of umbelliferone-4-acetic acid as protonophores in bilayer lipid membranes and ALDH2-dependent soft uncouplers in rat liver mitochondria. Bioelectrochemistry, >>


21. Rokitskaya Tatyana I., Aleksandrova Ekaterina V., Korshunova Galina A., Khailova Ljudmila S., Tashlitsky Vadim N., Luzhkov Victor B., Antonenko Yuri N. (2022) Membrane Permeability of Modified Butyltriphenylphosphonium Cations. Journal of Physical Chemistry B, >>


22. Žuna Kristina, Jovanovic Olga, Khailova Ljudmila S., Škulj Sanja, Brkljaˇca Zlatko, Jürgen Kreiter, Kotova Elena A., Vazdar Mario, Antonenko Yuri N., Pohl Elena E. (2021) Mitochondrial Uncoupling Proteins (UCP1-UCP3) and Adenine Nucleotide Translocase (ANT1) Enhance the Protonophoric Action of 2,4-Dinitrophenol in Mitochondria and Planar Bilayer Membranes. Biomolecules, >>


23. Terekhova Natalia V., Khailova Lyudmila S., Rokitskaya Tatyana I., Nazarov Pavel A., Islamov Daut R., Usachev Konstantin S., Tatarinov Dmitry A., Mironov Vladimir F., Kotova Elena A., Antonenko Yuri N. (2021) Trialkyl(vinyl)phosphonium Chlorophenol Derivatives as Potent Mitochondrial Uncouplers and Antibacterial Agents. ACS Omega, >>


24. Firsov Alexander M., Popova Ludmila B., Khailova Ljudmila S., Nazarov Pavel A., Kotova Elena A., Antonenko Yuri N. (2021) Protonophoric action of BAM15 on planar bilayers, liposomes, mitochondria, bacteria and neurons. Bioelectrochemistry, >>


25. Chelombitko Maria A., Firsov Alexander M., Kotova Elena A., Rokitskaya Tatyana I., Khailova Ljudmila S., Popova Lyudmila B., Chernyak Boris V., Antonenko Yuri N. (2020) Usnic acid as calcium ionophore and mast cells stimulator. Biochimica et Biophysica Acta - Biomembranes, >>


26. Goleva Tatyana N., Lyamzaev Konstantin G., Rogov Anton G., Khailova Ljudmila S., Epremyan Khoren K., Shumakovich Galina P., Domnina Lidia V., Ivanova Olga Yu, Marmiy Natalia V., Zinevich Tatiana V., Esipov Dmitry S., Zvyagilskaya Renata A., Skulachev Vlad (2020) Mitochondria-targeted 1,4-naphthoquinone (SkQN) is a powerful prooxidant and cytotoxic agent. Biochimica et Biophysica Acta - Bioenergetics, >>